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Werner et al. reported a polymeric nanoparticle formulation of docetaxel (Dtxl) targeted to the folate receptor (FT-NP Dtxl), and showed higher intracellular uptake by FR-overexpressing KB cells, compared to Dtxl or non-targeted NP Dtxl. Biocompatible and biodegradable poly lactic-co-glycolic acid (PLGA) nanoparticles encapsulated the hydrophobic Dtxl with lipids (lecithin), and lipid-PEG on the surface prevented protein adsorption, with the addition of a surface coating of folate.. In conclusion, the findings of this meta-analysis suggests that miR-423 rs6505162 polymorphism may play a role in protection against cancer. More well-designed studies are required to elucidate the exact role of miR-432 polymorphism on cancer development.. War II. Half of the Nobel Prize in Physics was shared in 1989 by two

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